VMA21 antibody

Catalog No. ABIN7254226

Product Details anti-VMA21 Antibody

Target: VMA21 (Vacuolar H+-ATPase Homolog (VMA21))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VMA21 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human VMA21

Isotype: IgG

Application Details

Application Notes: IHC 1:150-1:500, IF 1: 50-1:200, ELISA 1:5000-1:240000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for VMA21

Target: VMA21 (Vacuolar H+-ATPase Homolog (VMA21))

Alternative Name: VMA21 (VMA21 Products)

Background: This gene encodes a chaperone for assembly of lysosomal vacuolar ATPase. Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. Associates with the V0 complex of the vacuolar ATPase (V-ATPase). MEAX is a childhood-onset disease characterized by progressive vacuolation and atrophy of skeletal muscle. It is inherited in recessive fashion, affecting boys and sparing carrier females. Onset is in childhood, and patients exhibit weakness of the proximal muscles of the lower extremities, progressing slowly to involve other skeletal muscle groups over time.

UniProt: Q3ZAQ7