VGLL1 antibody

Catalog No. ABIN7254214

Product Details anti-VGLL1 Antibody

Target: VGLL1 (Vestigial Like 1 (VGLL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VGLL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human VGLL1

Isotype: IgG

Application Details

Application Notes: WB 1:2000-1:10000 ELISA 1:2000-1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for VGLL1

Target: VGLL1 (Vestigial Like 1 (VGLL1))

Alternative Name: VGLL1 (VGLL1 Products)

Synonyms: TDU antibody, VGL1 antibody, RGD1564038 antibody, VGLL1 antibody, vgl1 antibody, Tondu antibody, vestigial like family member 1 antibody, vestigial-like family member 1 antibody, VGLL1 antibody, Vgll1 antibody, vgll1 antibody

Background: The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 29 kDa

UniProt: Q99990