PRKCSH antibody

Catalog No. ABIN7254184

Product Details anti-PRKCSH Antibody

Target: PRKCSH (Protein Kinase C Substrate 80K-H (PRKCSH))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKCSH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human PRKCSH

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.32 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRKCSH

Target: PRKCSH (Protein Kinase C Substrate 80K-H (PRKCSH))

Alternative Name: PRKCSH (PRKCSH Products)

Synonyms: AGE-R2 antibody, G19P1 antibody, PCLD antibody, PKCSH antibody, PLD1 antibody, 80K-H antibody, VASAP-60 antibody, zgc:55653 antibody, prkcsh antibody, MGC75615 antibody, MGC82696 antibody, PRKCSH antibody, protein kinase C substrate 80K-H antibody, protein kinase C substrate 80K-H L homeolog antibody, phospholipase D1 antibody, PRKCSH antibody, Prkcsh antibody, prkcsh antibody, prkcsh.L antibody, Bm1_42055 antibody, LOC100304710 antibody, LOC100526729 antibody, PLD1 antibody

Background: This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.PRKCSH (Protein Kinase C Substrate 80K-H) is a Protein Coding gene. Diseases associated with PRKCSH include Polycystic Liver Disease and Polycystic Kidney And Hepatic Disease. Among its related pathways are Advanced glycosylation endproduct receptor signaling and Innate Immune System. GO annotations related to this gene include calcium ion binding and ion channel binding.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 59 kDa

UniProt: P14314

Pathways: Cellular Glucan Metabolic Process, Methionine Biosynthetic Process