ASNA1 antibody

Catalog No. ABIN7254112

Product Details anti-ASNA1 Antibody

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASNA1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human ASNA1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.26 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ASNA1

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Alternative Name: ASNA1 (ASNA1 Products)

Synonyms: ARSA-I antibody, ARSA1 antibody, ASNA-I antibody, GET3 antibody, TRC40 antibody, hASNA-I antibody, 1810048H22Rik antibody, ArsA antibody, wu:fd05d03 antibody, zgc:56540 antibody, zgc:86799 antibody, arsa-i antibody, arsa1 antibody, ASNA1 antibody, asna1 antibody, MGC146316 antibody, arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) antibody, arsenical pump-driving ATPase antibody, pseudo antibody, ATPase ASNA1 homolog antibody, arsenite-translocating ATPase; arsenical resistance ATPase; arsenite-transporting ATPase antibody, arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) S homeolog antibody, L-asparaginase antibody, ATPase asna-1 antibody, ASNA1 antibody, ATEG_04670 antibody, arsA2 antibody, arsA antibody, HCAG_00048 antibody, LOC5574421 antibody, CC1G_08655 antibody, CpipJ_CPIJ005690 antibody, PTRG_02265 antibody, pKlebpneu12_p77 antibody, UREG_07455 antibody, BDBG_06308 antibody, MCYG_00630 antibody, LOC100284977 antibody, Asna1 antibody, asna1 antibody, asna1.S antibody, MGYG_01332 antibody, asnA1 antibody, Tsp_06776 antibody, asna-1 antibody

Background: ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth,increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition,ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.

UniProt: O43681

Pathways: Positive Regulation of Peptide Hormone Secretion