MRPL22 antibody

Catalog No. ABIN7253878

Product Details anti-MRPL22 Antibody

Target: MRPL22 (Mitochondrial Ribosomal Protein L22 (MRPL22))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL22 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human MRPL22

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.02 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MRPL22

Target: MRPL22 (Mitochondrial Ribosomal Protein L22 (MRPL22))

Alternative Name: MRPL22 (MRPL22 Products)

Synonyms: L22mt antibody, MRP-L22 antibody, MRP-L25 antibody, RPML25 antibody, E030011D16Rik antibody, HSPC158 antibody, Rpml25 antibody, GB10944 antibody, DDBDRAFT_0205817 antibody, DDBDRAFT_0267022 antibody, DDB_0205817 antibody, DDB_0267022 antibody, zgc:171911 antibody, CG4742 antibody, Dmel\\CG4742 antibody, L22 antibody, mitochondrial ribosomal protein L22 antibody, 39S ribosomal protein L22, mitochondrial antibody, mitochondrial 54S ribosomal protein YmL22 antibody, ribosomal protein L22, mitochondrial antibody, mitochondrial ribosomal protein subunit L22 antibody, MRPL22 antibody, Mrpl22 antibody, LOC413121 antibody, mrpl22 antibody, CAALFM_C403410WA antibody, mRpL22 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 24 kDa

UniProt: Q9NWU5