Dihydrofolate Reductase antibody

Catalog No. ABIN7253152

Product Details anti-Dihydrofolate Reductase Antibody

Target: Dihydrofolate Reductase (DHFR)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dihydrofolate Reductase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human DHFR

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Dihydrofolate Reductase

Target: Dihydrofolate Reductase (DHFR)

Alternative Name: DHFR (DHFR Products)

Synonyms: DHFR antibody, F10_orf160 antibody, ECK0049 antibody, JW0047 antibody, tmrA antibody, cb595 antibody, zgc:86637 antibody, DDBDRAFT_0187132 antibody, DDBDRAFT_0230113 antibody, DDB_0187132 antibody, DDB_0230113 antibody, CG14887 antibody, Dmel\\CG14887 antibody, dhfr antibody, DHFRP1 antibody, DYR antibody, 8430436I03Rik antibody, AA607882 antibody, AI662710 antibody, AW555094 antibody, Dhfr1 antibody, confers resistance to sulfonamides antibody, dihydrofolate reductase antibody, dihydrofolate reductase DhfR antibody, Dihydrofolate reductase antibody, dhfr antibody, DHFR antibody, dhfR antibody, folA antibody, dfrA antibody, LOC707382 antibody, CNJ01940 antibody, DDB_G0286755 antibody, Dhfr antibody, Mesil_0096 antibody, Arch_0408 antibody, Fbal_3367 antibody, Ilyop_0482 antibody, Lbys_2007 antibody, Riean_0733 antibody, Mrub_1855 antibody, Poras_0766 antibody, Halhy_3552 antibody, Mesop_3614 antibody, LOC609048 antibody

Background: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 21 kDa

UniProt: P00374

Pathways: Mitotic G1-G1/S Phases