9430068D06Rik antibody, H3.3B antibody, H3 histone, family 3B antibody, H3 histone family member 3B antibody, H3f3b antibody, H3F3B antibody
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.