TLE6 antibody

Catalog No. ABIN7252918

Product Details anti-TLE6 Antibody

Target: TLE6 (Transducin-Like Enhancer of Split 6 (TLE6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE6 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human TLE6

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.38 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TLE6

Target: TLE6 (Transducin-Like Enhancer of Split 6 (TLE6))

Alternative Name: TLE6 (TLE6 Products)

Synonyms: GRG6 antibody, 1810057E06Rik antibody, Grg6 antibody, transducin like enhancer of split 6 antibody, transducin-like enhancer of split 6 antibody, TLE6 antibody, Tle6 antibody

Background: This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants.

UniProt: Q9H808

Pathways: WNT Signaling