Dystrobrevin beta antibody (AA 261-370)

Catalog No. ABIN700630

Product Details anti-Dystrobrevin beta Antibody

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Binding Specificity: AA 261-370

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dystrobrevin beta antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody may cross-react with DTNA based upon a 75 % sequence similarity across the immunogen sequence range.

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DTNB

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Dystrobrevin beta

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Alternative Name: DTNB (DTNB Products)

Synonyms: DTNB antibody, bdtn antibody, btnb antibody, dtnb antibody, GDTN antibody, dtng antibody, gtnb antibody, wu:fc61h11 antibody, dystrobrevin beta antibody, dystrobrevin, beta b antibody, dystrobrevin, beta antibody, dystrobrevin, beta a antibody, DTNB antibody, dtnbb antibody, Dtnb antibody, dtnba antibody, dtnb antibody

Background:

Synonyms: Dystrobrevin beta, DTN-B, Beta-dystrobrevin, DTNB

Background: Dystrobrevin beta is a component of the dystrophin-associated protein complex and interacts with dystrophin short form DP71, syntrophins SNTG1 and SNTG2. It localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. 4 isoforms produced by alternative splicing have been identified.

Gene ID: 1838

UniProt: O60941