EDARADD antibody

Catalog No. ABIN7252072

Product Details anti-EDARADD Antibody

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDARADD antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Full length fusion protein

Isotype: IgG

Application Details

Application Notes: IHC 1:35-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EDARADD

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Alternative Name: EDARADD (EDARADD Products)

Synonyms: 1810032E07Rik antibody, 5830469M23Rik antibody, A630043P06 antibody, cr antibody, ECTD11A antibody, ECTD11B antibody, ED3 antibody, EDA3 antibody, EDAR (ectodysplasin-A receptor)-associated death domain antibody, EDAR associated death domain antibody, Edaradd antibody, EDARADD antibody

Background: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

UniProt: Q8WWZ3

Pathways: Ubiquitin Proteasome Pathway