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LRRC19 antibody

LRRC19 Reactivity: Human, Mouse ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7252060
  • Target See all LRRC19 Antibodies
    LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))
    Reactivity
    • 47
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 47
    Rabbit
    Clonality
    • 47
    Polyclonal
    Conjugate
    • 12
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LRRC19 antibody is un-conjugated
    Application
    • 21
    • 20
    • 13
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of human LRRC19
    Isotype
    IgG
    Top Product
    Discover our top product LRRC19 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.1 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))
    Alternative Name
    LRRC19 (LRRC19 Products)
    Synonyms
    9130022A01Rik antibody, AI314124 antibody, AL022954 antibody, AW261791 antibody, leucine rich repeat containing 19 antibody, LRRC19 antibody, Lrrc19 antibody
    Background
    LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
    Molecular Weight

    Observed_MW: Refer to figures

    Calculated_MW: 42 kDa

    UniProt
    Q9H756
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