NDUFB11 antibody

Catalog No. ABIN7252021

Product Details anti-NDUFB11 Antibody

Target: NDUFB11 (NADH Dehydrogenase (Ubiquinone) 1 beta Subcomplex, 11, 17.3kDa (NDUFB11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFB11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Full length fusion protein

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NDUFB11

Target: NDUFB11 (NADH Dehydrogenase (Ubiquinone) 1 beta Subcomplex, 11, 17.3kDa (NDUFB11))

Alternative Name: NDUFB11 (NDUFB11 Products)

Synonyms: CI-ESSS antibody, ESSS antibody, NP17.3 antibody, Np15 antibody, P17.3 antibody, D5Bwg0566e antibody, D5Bwg0577e antibody, NP15.6 antibody, RGD1563698 antibody, NADH:ubiquinone oxidoreductase subunit B11 antibody, NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11 antibody, NDUFB11 antibody, Ndufb11 antibody

Background: Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 17 kDa

UniProt: Q9NX14