FBXO32 antibody
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- Target See all FBXO32 Antibodies
- FBXO32 (F-Box Protein 32 (FBXO32))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FBXO32 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Fusion protein of human FBXO32
- Isotype
- IgG
- Top Product
- Discover our top product FBXO32 Primary Antibody
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- Application Notes
- WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.02 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FBXO32 (F-Box Protein 32 (FBXO32))
- Alternative Name
- FBXO32 (FBXO32 Products)
- Synonyms
- MGC56479 antibody, zgc:56479 antibody, Fbx32 antibody, MAFbx antibody, 4833442G10Rik antibody, AI430017 antibody, ATROGIN1 antibody, Gm20361 antibody, Atrogin1 antibody, F-box protein 32 antibody, fbxo32 antibody, FBXO32 antibody, Fbxo32 antibody
- Background
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 42 kDa
- UniProt
- Q969P5
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