TRMT112 antibody

Catalog No. ABIN7251445

Product Details anti-TRMT112 Antibody

Target: TRMT112 (tRNA Methyltransferase 11-2 (TRMT112))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMT112 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human TRMT112

Isotype: IgG

Application Details

Application Notes: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRMT112

Target: TRMT112 (tRNA Methyltransferase 11-2 (TRMT112))

Alternative Name: TRMT112 (TRMT112 Products)

Synonyms: 0610038D11Rik antibody, Trm112p antibody, HSPC152 antibody, HSPC170 antibody, TRM112 antibody, TRMT11-2 antibody, TRM112L antibody, UPF0315 antibody, tRNA methyltransferase 11-2 antibody, tRNA methyltransferase subunit 11-2 antibody, Trmt112 antibody, TRMT112 antibody

Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

UniProt: Q9UI30