Laminin alpha 5 antibody

Catalog No. ABIN7251199

Product Details anti-Laminin alpha 5 Antibody

Target: Laminin alpha 5 (LAMA5) (Laminin, alpha 5 (LAMA5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Laminin alpha 5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthesized peptide derived from the Internal region of human Laminin alpha-5

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Laminin alpha 5

Target: Laminin alpha 5 (LAMA5) (Laminin, alpha 5 (LAMA5))

Alternative Name: Laminin alpha5 (LAMA5 Products)

Synonyms: cb402 antibody, sb:cb402 antibody, im:7138247 antibody, wu:fb81a10 antibody, AA408760 antibody, AA408762 antibody, AI853660 antibody, [a]5 antibody, laminin-511 antibody, mKIAA0533 antibody, laminin subunit alpha 5 antibody, laminin, alpha 5 antibody, LAMA5 antibody, lama5 antibody, Lama5 antibody

Background: Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.

Molecular Weight:

Observed_MW: 400 kDa

Calculated_MW: 400 kDa

UniProt: O15230

Pathways: Cell-Cell Junction Organization