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JAK3 antibody

JAK3 Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7251187
  • Target See all JAK3 Antibodies
    JAK3 (Janus Kinase 3 (JAK3))
    Reactivity
    • 83
    • 48
    • 18
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 79
    • 6
    Rabbit
    Clonality
    • 70
    • 15
    Polyclonal
    Conjugate
    • 31
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This JAK3 antibody is un-conjugated
    Application
    • 49
    • 29
    • 17
    • 14
    • 14
    • 12
    • 8
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthesized peptide derived from human JAK3 around the non-phosphorylation site of Tyr785.
    Isotype
    IgG
    Top Product
    Discover our top product JAK3 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    JAK3 (Janus Kinase 3 (JAK3))
    Alternative Name
    JAK3 (JAK3 Products)
    Synonyms
    JAK-3 antibody, JAK3_HUMAN antibody, JAKL antibody, L-JAK antibody, LJAK antibody, fae antibody, wil antibody, RATJAK3 antibody, JAK antibody, Janus kinase 3 antibody, JAK3 antibody, Jak3 antibody
    Background
    The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
    Molecular Weight

    Observed_MW: 125 kDa

    Calculated_MW: 125 kDa

    UniProt
    P52333
    Pathways
    JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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