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PYCARD antibody

PYCARD Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7251046
  • Target See all PYCARD Antibodies
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Reactivity
    • 56
    • 9
    • 8
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 47
    • 7
    • 3
    Rabbit
    Clonality
    • 46
    • 11
    Polyclonal
    Conjugate
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PYCARD antibody is un-conjugated
    Application
    • 39
    • 22
    • 15
    • 12
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthesized peptide derived from the N-terminal region of human ASC
    Isotype
    IgG
    Top Product
    Discover our top product PYCARD Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Alternative Name
    PYCARD (PYCARD Products)
    Synonyms
    ASC antibody, CARD5 antibody, TMS antibody, TMS-1 antibody, TMS1 antibody, 9130417A21Rik antibody, Asc antibody, TNS1 antibody, masc antibody, asc1 antibody, zAsc antibody, zgc:109874 antibody, PYD and CARD domain containing antibody, PYCARD antibody, Pycard antibody, pycard antibody
    Background
    Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
    Molecular Weight

    Observed_MW: 21 kDa

    Calculated_MW: 22 kDa

    UniProt
    Q9ULZ3
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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