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Beclin 1 antibody
BECN1
Reactivity: Human, Mouse, Rat
WB, IHC (p)
Host: Mouse
Monoclonal
3C6
unconjugated
Product Details anti-Beclin 1 Antibody
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Target
See all Beclin 1 (BECN1) Antibodies
Beclin 1 (BECN1)
(Beclin 1, Autophagy Related (BECN1))
Reactivity
All reactivities for Beclin 1 antibodies
Human, Mouse, Rat
Host
All hosts for Beclin 1 antibodies
Mouse
Clonality
All clonalities for Beclin 1 antibodies
Monoclonal
Conjugate
All conjugates for Beclin 1 antibodies
This Beclin 1 antibody is un-conjugated
Application
All applications for Beclin 1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Characteristics
Monoclonal Antibody
Purification
Protein A purification
Immunogen
Synthetic Peptide of Beclin-1
Clone
3C6
Isotype
IgG
Top Product
Discover our top product BECN1 Primary Antibody
Alternatives
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anti-Beclin 1, Autophagy Related (BECN1) (AA 201-330) antibody
BECN1
Reactivity: Human, Mouse, Rat
WB, ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB 1:1000-2000, IHC 1:100-200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Beclin 1
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Target
Beclin 1 (BECN1)
(Beclin 1, Autophagy Related (BECN1))
Alternative Name
BECN1 (BECN1 Products )
Synonyms
beclin-1 antibody, atg6 antibody, vps30 antibody, beclin1 antibody, Beclin-1 antibody, becn1 antibody, zgc:73097 antibody, ATG6 antibody, VPS30 antibody, 4921513J16Rik antibody, 5430417M23Rik antibody, Atg6 antibody, beclin 1 antibody, beclin 1, autophagy related antibody, beclin 1 protein antibody, beclin-1 antibody, beclin family protein antibody, beclin 1, autophagy related L homeolog antibody, BECN1 antibody, becn1 antibody, atg6 antibody, CpipJ_CPIJ011087 antibody, PTRG_07825 antibody, SJAG_01876 antibody, Becn1 antibody, becn1.L antibody
Background
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Molecular Weight
60 kDa
UniProt
Q14457
Pathways
Autophagy
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