TUBG1 antibody

Catalog No. ABIN7250341

Product Details anti-TUBG1 Antibody

Target: TUBG1 (Tubulin, gamma 1 (TUBG1))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Characteristics: Monoclonal Antibody

Purification: Protein A purification

Immunogen: Synthetic Peptide of Gamma Tubulin

Clone: 3E4

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000, IHC 1:100-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TUBG1

Target: TUBG1 (Tubulin, gamma 1 (TUBG1))

Alternative Name: gamma-Tubulin1 (TUBG1) (TUBG1 Products)

Background: This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. TUBG1 (Tubulin Gamma 1) is a Protein Coding gene. Diseases associated with TUBG1 include Cortical Dysplasia, Complex, With Other Brain Malformations 4 and Reducing Body Myopathy. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include GTP binding and structural constituent of cytoskeleton. An important paralog of this gene is TUBG2.

Molecular Weight: 50 kDa

UniProt: P23258

Pathways: Microtubule Dynamics, M Phase