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PRKAA1 antibody
PRKAA1
Reactivity: Human, Mouse, Rat
WB, IHC (p)
Host: Mouse
Monoclonal
6B6
unconjugated
Product Details anti-PRKAA1 Antibody
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Target
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PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Reactivity
All reactivities for PRKAA1 antibodies
Human, Mouse, Rat
Host
All hosts for PRKAA1 antibodies
Mouse
Clonality
All clonalities for PRKAA1 antibodies
Monoclonal
Conjugate
All conjugates for PRKAA1 antibodies
This PRKAA1 antibody is un-conjugated
Application
All applications for PRKAA1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Characteristics
Monoclonal Antibody
Purification
Protein A purification
Immunogen
Synthetic Peptide
Clone
6B6
Isotype
IgG
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Discover our top product PRKAA1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:1000-2000, IHC 1:50-100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PRKAA1
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Target
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Alternative Name
AMPK alpha1 (PRKAA1 Products )
Synonyms
AMPK antibody, AMPKa1 antibody, cb116 antibody, im:7154392 antibody, sb:cb130 antibody, wu:fa94c10 antibody, AMPK1 antibody, AMPKalpha1 antibody, AI194361 antibody, AI450832 antibody, AL024255 antibody, C130083N04Rik antibody, ampk antibody, ampka1 antibody, PRKAA1 antibody, protein kinase AMP-activated catalytic subunit alpha 1 antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antibody, PRKAA1 antibody, prkaa1 antibody, Prkaa1 antibody, prkaa1.L antibody
Background
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
Molecular Weight
63 kDa
UniProt
Q13131
Pathways
AMPK Signaling , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process , Warburg Effect
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