beta Catenin antibody
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- Target See all beta Catenin (CATNB) Antibodies
- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Reactivity
- Human, Mouse, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This beta Catenin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Characteristics
- Monoclonal Antibody
- Purification
- Protein A purification
- Immunogen
- Recombinant Protein
- Clone
- 2E4
- Isotype
- IgG
- Top Product
- Discover our top product CATNB Primary Antibody
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anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Xenopus laevis WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibodyCATNB Reactivity: Human, Mouse, Rat WB, FACS, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 661-781) antibodyCATNB Reactivity: Human, Mouse, Rat, Pig, Zebrafish (Danio rerio) WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB Reactivity: Human, Mouse, Rat, Chicken, Cow, Dog, Pig, Rabbit, Sheep, Monkey, Hamster, Avian, Cat, Donkey, Goat, Guinea Pig, Horse WB, IF Host: Goat Polyclonal unconjugated
anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibodyCATNB Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reactivity: Human, Mouse, Rat WB, IF, IHC (p) Host: Mouse Monoclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C901 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reactivity: Human, Mouse, Hamster WB, FACS, IP, ICC Host: Mouse Monoclonal EM-22 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reactivity: Human, Mouse, Rat WB, IHC Host: Mouse Monoclonal 4A3H3 unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- beta Catenin (CATNB) (Catenin, beta (CATNB))
- Alternative Name
- Catenin beta (CATNB Products)
- Synonyms
- Bfc antibody, Catnb antibody, Mesc antibody, CTNNB antibody, MRD19 antibody, armadillo antibody, ctnnb antibody, id:ibd2058 antibody, wu:fb73e10 antibody, wu:fi81c06 antibody, wu:fk25h01 antibody, beta-catenin antibody, ctnnb1 antibody, CHBCAT antibody, catenin (cadherin associated protein), beta 1 antibody, catenin beta 1 antibody, catenin (cadherin-associated protein), beta 1 antibody, catenin beta 1 L homeolog antibody, Ctnnb1 antibody, CTNNB1 antibody, ctnnb1 antibody, ctnnb1.L antibody
- Background
- Key dowstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes.Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
- Molecular Weight
- 92 kDa
- UniProt
- P35222
- Pathways
- Peptide Hormone Metabolism
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