HAO1 antibody

Catalog No. ABIN7250251

Product Details anti-HAO1 Antibody

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Reactivity: Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This HAO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Characteristics: Monoclonal Antibody

Purification: Protein A purification

Immunogen: Recombinant Protein

Clone: 3B2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:300, IF 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HAO1

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Alternative Name: HAO1 (HAO1 Products)

Synonyms: hao1 antibody, GOX antibody, GOX1 antibody, HAOX1 antibody, Gox1 antibody, XDH1 antibody, Hao-1 antibody, hydroxyacid oxidase 1 antibody, hydroxyacid oxidase (glycolate oxidase) 1 antibody, hydroxyacid oxidase (glycolate oxidase) 1 L homeolog antibody, hydroxyacid oxidase 1, liver antibody, CpipJ_CPIJ013711 antibody, THEYE_A0075 antibody, hao1 antibody, HAO1 antibody, hao1.L antibody, Hao1 antibody

Background: This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. HAO1 (Hydroxyacid Oxidase 1) is a Protein Coding gene. Diseases associated with HAO1 include Lactocele and Primary Hyperoxaluria. Among its related pathways are Glyoxylate metabolism and glycine degradation and Peroxisome. GO annotations related to this gene include receptor binding and FMN binding. An important paralog of this gene is HAO2.

Molecular Weight: 41 kDa

UniProt: Q9UJM8

Pathways: Monocarboxylic Acid Catabolic Process