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CD16 antibody

CD16 Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal 2B1 unconjugated
Catalog No. ABIN7250149
  • Target See all CD16 Antibodies
    CD16
    Reactivity
    • 129
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    • 9
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    • 1
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    Human
    Host
    • 112
    • 25
    • 14
    • 1
    Mouse
    Clonality
    • 127
    • 23
    • 1
    Monoclonal
    Conjugate
    • 54
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    • 14
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    • 6
    • 3
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This CD16 antibody is un-conjugated
    Application
    • 125
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    • 15
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    • 3
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Characteristics
    Monoclonal Antibody
    Purification
    Protein A purification
    Immunogen
    Synthetic Peptide
    Clone
    2B1
    Isotype
    IgG
    Top Product
    Discover our top product CD16 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CD16
    Alternative Name
    CD16 (CD16 Products)
    Synonyms
    Fcgr3 antibody, Fcgr3a antibody, CD16 antibody, FCGR3 antibody, FCGR3@ antibody, CD16b antibody, FCG3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, FcRIII antibody, Fc fragment of IgG, low affinity IIa, receptor antibody, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antibody, Fc fragment of IgG receptor IIIb antibody, Fc fragment of IgG receptor IIIa antibody, Fc receptor, IgG, low affinity III antibody, Fc-gamma RIII antibody, Fcgr2a antibody, FCGR3A antibody, FCGR3B antibody, Fcgr3 antibody, FCGR3 antibody
    Background
    This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.
    Molecular Weight

    Observed_MW: 45 kDa

    Calculated_MW: 28 kDa

    UniProt
    P08637, O75015
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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