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PERK antibody
EIF2AK3
Reactivity: Human
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PERK Antibody
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Target
See all PERK (EIF2AK3) Antibodies
PERK (EIF2AK3)
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
Reactivity
All reactivities for PERK antibodies
Human
Host
All hosts for PERK antibodies
Rabbit
Clonality
All clonalities for PERK antibodies
Polyclonal
Conjugate
All conjugates for PERK antibodies
This PERK antibody is un-conjugated
Application
All applications for PERK antibodies
Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
KLH conjugated Synthetic peptide corresponding to Human PERK
Isotype
IgG
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Discover our top product EIF2AK3 Primary Antibody
Alternatives
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anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (pThr980) antibody
EIF2AK3
Reactivity: Human, Mouse, Rat, Dog, Pig
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IHC 1:400-1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.4 mg/mL
Buffer
PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PERK
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Target
PERK (EIF2AK3)
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
Alternative Name
PERK (EIF2AK3 Products )
Synonyms
EIF2AK3 antibody, AI427929 antibody, Pek antibody, Perk antibody, PEK antibody, PERK antibody, WRS antibody, eukaryotic translation initiation factor 2 alpha kinase 3 antibody, EIF2AK3 antibody, Eif2ak3 antibody
Background
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
UniProt
Q9NZJ5
Pathways
Hormone Transport , ER-Nucleus Signaling , Positive Regulation of Endopeptidase Activity , Hepatitis C , Unfolded Protein Response
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