Caspase 1 antibody
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- Target See all Caspase 1 (CASP1) Antibodies
- Caspase 1 (CASP1)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caspase 1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse Caspase1
- Isotype
- IgG
- Top Product
- Discover our top product CASP1 Primary Antibody
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anti-Caspase 1 (CASP1) (AA 317-404) antibody
CASP1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-297) antibodyCASP1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 119-296) antibodyCASP1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-297) antibodyCASP1 Reactivity: Pig WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 1-311) antibodyCASP1 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 1-100) antibodyCASP1 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 3D2 unconjugated
anti-Caspase 1 (CASP1) (AA 135-152), (N-Term) antibodyCASP1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-269) antibodyCASP1 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-269) antibodyCASP1 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (C-Term) antibodyCASP1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:300-1:800
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.2 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Caspase 1 (CASP1)
- Alternative Name
- CASP1 (CASP1 Products)
- Background
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
- Molecular Weight
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Observed_MW: 45-47 kDa,30 kDa,35 kDa
Calculated_MW: 45 kDa
- UniProt
- P29466, P29452, P43527
- Pathways
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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