NR3C2 antibody
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- Target See all NR3C2 Antibodies
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR3C2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor
- Isotype
- IgG
- Top Product
- Discover our top product NR3C2 Primary Antibody
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.3 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
- Alternative Name
- Mineralocorticoid receptor (NR3C2 Products)
- Synonyms
- mr antibody, si:ch211-189l17.1 antibody, LOC100302443 antibody, NR3C2 antibody, LOC443144 antibody, MLR antibody, MR antibody, MCR antibody, NR3C2VIT antibody, Mlr antibody, mlr antibody, nuclear receptor subfamily 3, group C, member 2 antibody, nuclear receptor subfamily 3 group C member 2 antibody, mineralocorticoid receptor antibody, nuclear receptor subfamily 3 group C member 2 L homeolog antibody, nr3c2 antibody, NR3C2 antibody, LOC443144 antibody, Nr3c2 antibody, nr3c2.L antibody
- Background
- This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 107 kDa
Calculated_MW: 107 kDa
- UniProt
- P08235
- Pathways
- ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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