beta Catenin antibody
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- Target See all beta Catenin (CATNB) Antibodies
- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Reactivity
- Human, Mouse, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This beta Catenin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Monoclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse beta-catenin
- Clone
- 4A3H3
- Isotype
- IgG
- Top Product
- Discover our top product CATNB Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IHC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 420 μg/mL
- Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- beta Catenin (CATNB) (Catenin, beta (CATNB))
- Alternative Name
- Catenin beta (CATNB Products)
- Background
- CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
- Molecular Weight
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Observed_MW: 92 kDa
Calculated_MW: 92 kDa
- UniProt
- P35222, Q02248, Q9WU82
- Pathways
- Peptide Hormone Metabolism
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