P2RX3 antibody

Catalog No. ABIN7249726

Product Details anti-P2RX3 Antibody

Target: P2RX3 (Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RX3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse P2X3

Isotype: IgG

Application Details

Application Notes: IHC 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 420 μg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for P2RX3

Target: P2RX3 (Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3))

Alternative Name: P2RX3 (P2RX3 Products)

Synonyms: P2X3 antibody, 4930513E20Rik antibody, P2RX3 antibody, fb99b08 antibody, p2rx3 antibody, p2x3 antibody, wu:fb99b08 antibody, zP2X3 antibody, zfP2X3 antibody, p2xr3.2 antibody, zP2X3.2 antibody, zgc:110486 antibody, purinergic receptor P2X 3 antibody, purinergic receptor P2X, ligand-gated ion channel, 3 antibody, purinergic receptor P2X, ligand-gated ion channel, 3a antibody, purinergic receptor P2X, ligand-gated ion channel, 3b antibody, P2RX3 antibody, P2rx3 antibody, p2rx3a antibody, p2rx3b antibody

Background: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

UniProt: Q3UR32, P49654