GTF3A antibody

Catalog No. ABIN7248899

Product Details anti-GTF3A Antibody

Target: GTF3A (General Transcription Factor IIIA (GTF3A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF3A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human GTF3A

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.68 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GTF3A

Target: GTF3A (General Transcription Factor IIIA (GTF3A))

Alternative Name: GTF3A (GTF3A Products)

Synonyms: 2010015D03Rik antibody, 2610111I01Rik antibody, 5330403M05Rik antibody, GTF3A antibody, TFIIIA antibody, gtf3a antibody, zgc:111799 antibody, AP2 antibody, general transcription factor III A antibody, general transcription factor IIIA antibody, general transcription factor 3A L homeolog antibody, general transcription factor IIIAa antibody, Gtf3a antibody, GTF3A antibody, gtf3a.L antibody, gtf3aa antibody

Background: The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 42 kDa

UniProt: Q92664