GPT2 antibody

Catalog No. ABIN7248875

Product Details anti-GPT2 Antibody

Target: GPT2 (Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPT2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human GPT2

Isotype: IgG

Application Details

Application Notes: IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.16 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GPT2

Target: GPT2 (Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2))

Alternative Name: GPT2 (GPT2 Products)

Synonyms: ALT2 antibody, GPT2 antibody, im:7150662 antibody, sb:cb580 antibody, zgc:165657 antibody, Cc2-5 antibody, 4631422C05Rik antibody, AU014768 antibody, AU041193 antibody, C87201 antibody, ALANINE AMINOTRANSFERASE 2 antibody, AtAlaAT2 antibody, AtAlaATm antibody, T10D10.20 antibody, T10D10_20 antibody, alanine aminotransferase 2 antibody, glutamic--pyruvic transaminase 2 antibody, glutamic pyruvate transaminase (alanine aminotransferase) 2 L homeolog antibody, glutamic pyruvate transaminase (alanine aminotransferase) 2 antibody, alanine aminotransferase 2 antibody, GPT2 antibody, gpt2.L antibody, gpt2 antibody, PTRG_06494 antibody, Gpt2 antibody, ALAAT2 antibody

Background: This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.

UniProt: Q8TD30