FOLR1 antibody
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- Target See all FOLR1 Antibodies
- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FOLR1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human FOLR1
- Isotype
- IgG
- Top Product
- Discover our top product FOLR1 Primary Antibody
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- Application Notes
- IHC 1:40-1:200, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2.28 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
- Alternative Name
- FOLR1 (FOLR1 Products)
- Background
- Folate receptor 1 (FOLR1),also known as folate receptor alpha or adult folate-binding protein (FBP),is a 38- kDa glycoprotein belonging to the folate receptor family . The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung,kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer,non-small cell lung cancer,breast cancer,kidney cancer and high-grade osteosarcoma .
- UniProt
- P15328
- Pathways
- Dicarboxylic Acid Transport
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