FBL4 antibody, FBL5 antibody, FBXL4 antibody, CG1839 antibody, Dmel\\CG1839 antibody, dFbxl4 antibody, 4732456I21 antibody, AI836810 antibody, zgc:92297 antibody, GB14438 antibody, F-box and leucine rich repeat protein 4 antibody, F box and leucine-rich-repeat gene 4 antibody, F-box and leucine-rich repeat protein 4 antibody, F-box/LRR-repeat protein 4 antibody, F-box/RNI-like superfamily protein antibody, FBXL4 antibody, Fbxl4 antibody, fbxl4 antibody, LOC551738 antibody, AT4G15475 antibody
Background
This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants.