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ZNF828 antibody

ZNF828 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7248329
  • Target See all ZNF828 Antibodies
    ZNF828 (Zinc Finger Protein 828 (ZNF828))
    Reactivity
    • 43
    • 21
    • 16
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 41
    • 2
    Rabbit
    Clonality
    • 43
    Polyclonal
    Conjugate
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZNF828 antibody is un-conjugated
    Application
    • 36
    • 13
    • 12
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human CHAMP1
    Isotype
    IgG
  • Application Notes
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ZNF828 (Zinc Finger Protein 828 (ZNF828))
    Alternative Name
    CHAMP1 (ZNF828 Products)
    Synonyms
    ZNF828 antibody, C13orf8 antibody, CAMP antibody, CHAMP antibody, AA675043 antibody, AI116001 antibody, D8Ertd457e antibody, D8Ertd569e antibody, Zfp828 antibody, Znf828 antibody, mKIAA1802 antibody, chromosome alignment maintaining phosphoprotein 1 antibody, CHAMP1 antibody, Champ1 antibody
    Background
    CHAMP1 (chromosome alignment maintaining phosphoprotein 1), also known as ZNF828 or C13orf8, is a 812 amino acid protein containing one C2H2-type zinc finger. CHAMP1 is required for the proper alignment of chromosomes during metaphase, undergoing CDK1-dependent phosphorylation at multiple sites during mitosis. The phosphorylation counteracts the negative chromosomal alignment regulation of the zinc-finger domain of CHAMP1. One region of CHAMP1, the FPE region, is responsible for spindle and kinetochore localization, which is essential for proper chromosome alignment. CHAMP1 interacts with MAD2L2, PGOZ, CBX1, CBX3 and CBX5, and may recruit CENPE and CENPF to the kinetochore. The CHAMP1 gene is located on chromosome 13 and is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat and chicken.
    UniProt
    Q96JM3
    Pathways
    Maintenance of Protein Location
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