ENPP2 antibody

Catalog No. ABIN7248311

Product Details anti-ENPP2 Antibody

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human ENPP2

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Alternative Name: ENPP2 (ENPP2 Products)

Synonyms: ATX antibody, ATX-X antibody, AUTOTAXIN antibody, LysoPLD antibody, NPP2 antibody, PD-IALPHA antibody, PDNP2 antibody, Npps2 antibody, PD-Ialpha antibody, Pdnp2 antibody, MGC132047 antibody, atx antibody, zgc:63550 antibody, autotaxin antibody, enpp2 antibody, enpp2a antibody, enpp2b antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog antibody, ENPP2 antibody, Enpp2 antibody, enpp2 antibody, enpp2.L antibody, enpp2.S antibody

Background: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

UniProt: Q13822