ZBTB10 antibody

Catalog No. ABIN7248218

Product Details anti-ZBTB10 Antibody

Target: ZBTB10 (Zinc Finger and BTB Domain-Containing Protein 10 (ZBTB10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human ZBTB10

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZBTB10

Target: ZBTB10 (Zinc Finger and BTB Domain-Containing Protein 10 (ZBTB10))

Alternative Name: ZBTB10 (ZBTB10 Products)

Synonyms: RINZF antibody, Rinzf antibody, zinc finger and BTB domain containing 10 antibody, ZBTB10 antibody, Zbtb10 antibody

Background: RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98 % homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 95 kDa

UniProt: Q96DT7