MBL2 antibody

Catalog No. ABIN7248173

Product Details anti-MBL2 Antibody

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBL2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human MBL2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MBL2

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Alternative Name: MBL2 (MBL2 Products)

Synonyms: COLEC1 antibody, HSMBPC antibody, MBL antibody, MBL2D antibody, MBP antibody, MBP-C antibody, MBP1 antibody, MBPD antibody, pMBP-27 antibody, mbl2 antibody, MBL1 antibody, cMBl antibody, collectin antibody, Ab2-001 antibody, Ab2-011 antibody, L-MBP antibody, MBL-C antibody, COLEC2 antibody, mbl antibody, etID42583.2 antibody, fb68b07 antibody, hbl3 antibody, wu:fb68b07 antibody, zgc:109836 antibody, mannose binding lectin 2 antibody, Mannose-binding protein C antibody, mannose-binding lectin (protein C) 2, soluble antibody, mannose-binding lectin (protein C) 2 antibody, mannose-binding lectin family member 3, pseudogene antibody, MBL2 antibody, mbl2 antibody, Mbl2 antibody, MBL3P antibody

Background: MBL2 (Mannose Binding Lectin 2) is a Protein Coding gene. Diseases associated with MBL2 include Chronic Infections, Due To Mbl Deficiency and Pulmonary Tuberculosis. Among its related pathways are Complement Pathway and Innate Immune System. GO annotations related to this gene include calcium ion binding and calcium-dependent protein binding. An important paralog of this gene is SFTPD.This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.

UniProt: P11226

Pathways: Complement System, Positive Regulation of Immune Effector Process