COX17 antibody

Catalog No. ABIN7248020

Product Details anti-COX17 Antibody

Target: COX17 (COX17 Cytochrome C Oxidase Assembly Protein 17 (COX17))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX17 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human COX17

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:2000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COX17

Target: COX17 (COX17 Cytochrome C Oxidase Assembly Protein 17 (COX17))

Alternative Name: COX17 (COX17 Products)

Synonyms: AI037035 antibody, Tb03.48O8.160 antibody, zgc:103765 antibody, zgc:191605 antibody, DKFZp469A2113 antibody, COX17 antibody, Dopuin antibody, COX17, cytochrome c oxidase copper chaperone antibody, cytochrome c oxidase assembly protein 17 antibody, cytochrome c oxidase copper chaperone antibody, COX17 cytochrome c oxidase copper chaperone antibody, COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) antibody, COX17 homolog, cytochrome c oxidase assembly protein (yeast) antibody, COX17 cytochrome c oxidase assembly homolog antibody, COX17 antibody, Cox17 antibody, Tc00.1047053508153.994 antibody, Tb927.3.2650 antibody, PVX_111430 antibody, cox17 antibody

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92 % amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.

UniProt: Q14061