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HIPK3 antibody

HIPK3 Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7247966
  • Target See all HIPK3 Antibodies
    HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
    Reactivity
    Human, Mouse, Rat
    Host
    • 49
    Rabbit
    Clonality
    • 49
    Polyclonal
    Conjugate
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIPK3 antibody is un-conjugated
    Application
    • 25
    • 19
    • 18
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human HIPK3
    Isotype
    IgG
    Top Product
    Discover our top product HIPK3 Primary Antibody
  • Application Notes
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
    Alternative Name
    HIPK3 (HIPK3 Products)
    Synonyms
    HIPK3 antibody, pky antibody, yak1 antibody, dyrk6 antibody, fist3 antibody, MGC145460 antibody, DYRK6 antibody, FIST3 antibody, PKY antibody, YAK1 antibody, ANPK antibody, homeodomain interacting protein kinase 3 antibody, homeodomain interacting protein kinase 3 L homeolog antibody, HIPK3 antibody, hipk3.L antibody, hipk3 antibody, Hipk3 antibody
    Background
    Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
    UniProt
    Q9H422
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