RBM4 antibody

Catalog No. ABIN7247819

Product Details anti-RBM4 Antibody

Target: RBM4 (RNA Binding Motif Protein 4 (RBM4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human RBM4

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.72 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RBM4

Target: RBM4 (RNA Binding Motif Protein 4 (RBM4))

Alternative Name: RBM4 (RBM4 Products)

Synonyms: rbm4 antibody, rna-bp4 antibody, wu:fc31f07 antibody, wu:fc57h11 antibody, zgc:56302 antibody, LARK antibody, RBM4A antibody, ZCCHC21 antibody, ZCRB3A antibody, 4921506I22Rik antibody, Lark1 antibody, Mlark antibody, Rbm4a antibody, lark antibody, Rbm4 antibody, RNA binding motif protein 4.1 antibody, RNA binding motif protein 4 antibody, RNA-binding protein 14 antibody, RNA-binding protein lark antibody, rbm4.1 antibody, RBM4 antibody, LOC610648 antibody, Rbm4 antibody, LARK antibody

Background: RBM4,RNA-binding motif protein4,contains 2 RRM-type RNA-binding motif and a retroviral-type(RT) zinc finger. RNA-binding factor participates in number of aspects of cellular processes such as alternative splicing of pre-mRNA and translation regulation. RBM4 recruits eIF4A1 to stimulate IRES-dependent translation in responds to cellular stress. Once assembled at the rHRE,the HIF2A-RBM4-eIF4E2 complex captures the 5-prime cap and targets mRNAs to polysomes for active translation,thereby evading hypoxia-induced repression of protein synthesis.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 40 kDa

UniProt: Q9BWF3

Pathways: Regulation of Muscle Cell Differentiation, Photoperiodism