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HORMAD2 antibody

HORMAD2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7247717
  • Target See all HORMAD2 Antibodies
    HORMAD2 (HORMA Domain Containing 2 (HORMAD2))
    Reactivity
    • 16
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 14
    • 2
    Rabbit
    Clonality
    • 15
    • 1
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    This HORMAD2 antibody is un-conjugated
    Application
    • 10
    • 7
    • 2
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of human HORMAD2
    Isotype
    IgG
  • Application Notes
    IHC 1:50-1:200, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.32 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HORMAD2 (HORMA Domain Containing 2 (HORMAD2))
    Alternative Name
    HORMAD2 (HORMAD2 Products)
    Synonyms
    4930529M09Rik antibody, HORMA domain containing 2 antibody, HORMAD2 antibody, Hormad2 antibody
    Background
    Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).
    UniProt
    Q8N7B1
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