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RITA1 antibody
RITA1
Reactivity: Human
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RITA1 Antibody
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Target
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RITA1
(Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))
Reactivity
Human
Host
All hosts for RITA1 antibodies
Rabbit
Clonality
All clonalities for RITA1 antibodies
Polyclonal
Conjugate
All conjugates for RITA1 antibodies
This RITA1 antibody is un-conjugated
Application
ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Antigen affinity purification
Immunogen
Fusion protein of human RITA1
Isotype
IgG
Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.02 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for RITA1
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Target
RITA1
(Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))
Alternative Name
RITA1 (RITA1 Products )
Synonyms
AI853657 antibody, C86297 antibody, Rita antibody, RBPJ interacting and tubulin associated 1 antibody, Rita1 antibody
Background
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
UniProt
Q96K30
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