KRCC1 antibody

Catalog No. ABIN7247672

Product Details anti-KRCC1 Antibody

Target: KRCC1 (Lysine-Rich Coiled-Coil 1 (KRCC1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRCC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human KRCC1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.68 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KRCC1

Target: KRCC1 (Lysine-Rich Coiled-Coil 1 (KRCC1))

Alternative Name: KRCC1 (KRCC1 Products)

Synonyms: DKFZp468N1119 antibody, CHBP2 antibody, AA792894 antibody, RGD1306495 antibody, lysine rich coiled-coil 1 antibody, lysine-rich coiled-coil 1 antibody, KRCC1 antibody, Krcc1 antibody

Background: KRCC1 (lysine-rich coiled-coil 1), also known as CHBP2 (cryptogenic hepatitis-binding protein 2), is a 259 amino acid protein that is encoded by a gene located on human chromosome 2p11.2. Consisting of 237 million bases, chromosome 2 is the second largest human chromosome and encodes over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstrm syndrome, is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 31 kDa

UniProt: Q9NPI7