PSMA6 antibody

Catalog No. ABIN7247630

Product Details anti-PSMA6 Antibody

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human PSMA6

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.56 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSMA6

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Alternative Name: PSMA6 (PSMA6 Products)

Synonyms: IOTA antibody, PROS27 antibody, p27K antibody, psma6 antibody, psma6b antibody, zgc:91778 antibody, proteasome subunit alpha 6 antibody, proteasome (prosome, macropain) subunit, alpha type 6 antibody, proteasome subunit alpha 6a antibody, proteasome subunit alpha 6 L homeolog antibody, proteasome subunit alpha 6, like antibody, PSMA6 antibody, Psma6 antibody, psma6a antibody, psma6.L antibody, psma6l antibody

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 27 kDa

UniProt: P60900

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA