DNAJA4 antibody

Catalog No. ABIN7247618

Product Details anti-DNAJA4 Antibody

Target: DNAJA4 (DnaJ (Hsp40) Homolog, Subfamily A, Member 4 (DNAJA4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human DNAJA4

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DNAJA4

Target: DNAJA4 (DnaJ (Hsp40) Homolog, Subfamily A, Member 4 (DNAJA4))

Alternative Name: DNAJA4 (DNAJA4 Products)

Synonyms: MGC52928 antibody, MST104 antibody, MSTP104 antibody, PRO1472 antibody, 1110021L12Rik antibody, AV358213 antibody, Dj4 antibody, Hsj4 antibody, mmDjA4 antibody, DnaJ (Hsp40) homolog, subfamily A, member 4, gene 2 S homeolog antibody, DnaJ heat shock protein family (Hsp40) member A4 antibody, dnaja4.2.S antibody, DNAJA4 antibody, Dnaja4 antibody

Background: The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 45 kDa

UniProt: Q8WW22