ITGB1BP1 antibody

Catalog No. ABIN7247549

Product Details anti-ITGB1BP1 Antibody

Target: ITGB1BP1 (Integrin beta 1 Binding Protein 1 (ITGB1BP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB1BP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human ITGB1BP1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ITGB1BP1

Target: ITGB1BP1 (Integrin beta 1 Binding Protein 1 (ITGB1BP1))

Alternative Name: ITGB1BP1 (ITGB1BP1 Products)

Synonyms: si:dkey-27p7.1 antibody, zgc:123198 antibody, ICAP-1A antibody, ICAP-1B antibody, ICAP-1alpha antibody, ICAP1 antibody, ICAP1A antibody, ICAP1B antibody, AI449260 antibody, AU019480 antibody, Icap1 antibody, integrin subunit beta 1 binding protein 1 antibody, integrin beta 1 binding protein 1 antibody, Itgb1bp1 antibody, itgb1bp1 antibody, ITGB1BP1 antibody

Background: The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.

UniProt: O14713

Pathways: Tube Formation