KIAA0101 antibody

Catalog No. ABIN7247369

Product Details anti-KIAA0101 Antibody

Target: KIAA0101 (PAF) (PCNA Clamp Associated Factor (PAF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIAA0101 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human PCLAF

Isotype: IgG

Application Details

Application Notes: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KIAA0101

Target: KIAA0101 (PAF) (PCNA Clamp Associated Factor (PAF))

Alternative Name: PCLAF (PAF Products)

Synonyms: NS5ATP9 antibody, OEATC antibody, OEATC-1 antibody, OEATC1 antibody, PAF antibody, PAF15 antibody, p15(PAF) antibody, p15/PAF antibody, p15PAF antibody, paf antibody, Paf antibody, AA409629 antibody, Ns5apt9 antibody, Ns5atp9 antibody, mKIAA0101 antibody, Kiaa0101 antibody, PCNA clamp associated factor antibody, PCNA clamp associated factor S homeolog antibody, PCLAF antibody, pclaf antibody, pclaf.S antibody, Pclaf antibody

Background: PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.

UniProt: Q15004

Pathways: Chromatin Binding