Sorbs2 antibody

Catalog No. ABIN7247306

Product Details anti-Sorbs2 Antibody

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorbs2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human SORBS2

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:150-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.02 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Sorbs2

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Alternative Name: SORBS2 (Sorbs2 Products)

Synonyms: Argbp2 antibody, 2010203O03Rik antibody, 9430041O17Rik antibody, A530071H08 antibody, mKIAA0777 antibody, argbp2 antibody, pro0618 antibody, 9430041O17RIK antibody, DKFZp468F1119 antibody, ARGBP2 antibody, PRO0618 antibody, sorbin and SH3 domain containing 2 antibody, Sorbs2 antibody, SORBS2 antibody, sorbs2 antibody

Background: Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 124 kDa

UniProt: O94875