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ARIH2 antibody

ARIH2 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7247255
  • Target See all ARIH2 Antibodies
    ARIH2 (protein ariadne-2 homolog (ARIH2))
    Reactivity
    • 48
    • 20
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Human, Mouse
    Host
    • 43
    • 4
    • 1
    Rabbit
    Clonality
    • 45
    • 2
    Polyclonal
    Conjugate
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARIH2 antibody is un-conjugated
    Application
    • 35
    • 26
    • 22
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of human ARIH2
    Isotype
    IgG
    Top Product
    Discover our top product ARIH2 Primary Antibody
  • Application Notes
    WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.38 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ARIH2 (protein ariadne-2 homolog (ARIH2))
    Alternative Name
    ARIH2 (ARIH2 Products)
    Synonyms
    ARI2 antibody, TRIAD1 antibody, AI843547 antibody, UIP48 antibody, wu:fa09c12 antibody, zgc:64093 antibody, ariadne RBR E3 ubiquitin protein ligase 2 antibody, ariadne RBR E3 ubiquitin protein ligase 2 L homeolog antibody, ariadne homolog 2 (Drosophila) antibody, ARIH2 antibody, Arih2 antibody, arih2.L antibody, arih2 antibody
    Background
    TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
    Molecular Weight

    Observed_MW: Refer to figures

    Calculated_MW: 58 kDa

    UniProt
    O95376
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