Kcne3 antibody

Catalog No. ABIN7246949

Product Details anti-Kcne3 Antibody

Target: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kcne3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human KCNE3

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Kcne3

Target: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Alternative Name: KCNE3 (Kcne3 Products)

Synonyms: HOKPP antibody, HYPP antibody, MiRP2 antibody, 2210017H05Rik antibody, potassium voltage-gated channel subfamily E regulatory subunit 3 antibody, potassium voltage-gated channel, Isk-related subfamily, gene 3 antibody, KCNE3 antibody, Kcne3 antibody

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis.

UniProt: Q9Y6H6