GTF2A2 antibody

Catalog No. ABIN7246742

Product Details anti-GTF2A2 Antibody

Target: GTF2A2 (General Transcription Factor IIA, 2, 12kDa (GTF2A2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2A2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human GTF2A2

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.54 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GTF2A2

Target: GTF2A2 (General Transcription Factor IIA, 2, 12kDa (GTF2A2))

Alternative Name: GTF2A2 (GTF2A2 Products)

Synonyms: CG11639 antibody, Dmel\\CG11639 antibody, EG:BACR7A4.7 antibody, TFIIA antibody, tfiia-s-2 antibody, GTF2A2 antibody, DDBDRAFT_0186451 antibody, DDBDRAFT_0216276 antibody, DDB_0186451 antibody, DDB_0216276 antibody, zgc:110584 antibody, TFIIA-gamma antibody, TfIIg antibody, Tfiia2 antibody, HsT18745 antibody, TF2A2 antibody, LOC100136048 antibody, T2AG antibody, gtf2a2 antibody, CG11639 gene product from transcript CG11639-RA antibody, general transcription factor IIA subunit 2 antibody, transcription factor IIA, small chain antibody, general transcription factor IIA, 2 antibody, general transcription factor II A, 2 antibody, transcription initiation factor IIA subunit 2 antibody, TfIIA-S-2 antibody, GTF2A2 antibody, gtf2a2 antibody, Gtf2a2 antibody

Background: Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A, MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP, MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF, MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).

UniProt: P52657